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DOTA-tris(t-Bu)ester-C4-propanamido-maleimide amine-amine NCT02 induces ubiquitination of cyclin

SKU 57728640907
4.4
USD190.00 USD227.00

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Description

NCT02 induces ubiquitination of cyclin K (CCNK) and proteasomal degradation of CCNK and its complex partner CDK12

Product Name 2-chloro-5-(methoxy-d3)pyrimidine Synonyms CAS Number n/a Related CAS Molecular Formula C5H5ClN2O Molecular Weight 147

Product Name Thalidomide-C3-O-C2-Br Synonyms Thalidomide-4'-C3-O-C2-Br CAS Number n/a Related CAS Molecular Formula C18H19BrN2O5 Molecular Weight 423

676 SMILES CC(C)(C)OC(=O)NCCCCN1CCN(CCN2CCN(CCOCCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DOTA-tris(t-Bu)ester-C4-propanamido-maleimide amine-amine NCT02 induces ubiquitination of cyclinDOTA bifucational chelator containing a thiol reactive maleimide group, an alkyl linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA tris(t Bu)ester C4 propanamido maleimide Synonyms CAS Number Related CAS Molecular Formula

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